Fat-dissolving injections (lipolysis) – removing stubborn fat deposits

Some fatty deposits do not respond to either diet or exercise, no matter how hard you try. Lipolysis is an injection method used to selectively reduce localised fatty deposits on the face and body: double chin, stomach, flanks, thighs and upper arms. At Imedic poliklinika, we perform lipolysis with Lemon Bottle and Aqualyx. Lipolysis is not a weight loss method, but a local correction. Downtime is usually not needed, but swelling, tenderness and bruising may last for a few days, and results develop gradually in the weeks following the treatment.

Lipolysis – in brief

What it treatsLocalised fatty deposits on the face and body, most commonly the double chin
ProductsLemon Bottle and Aqualyx
AnaesthesiaAnaesthetic cream, as required
Duration of treatmentFrom a few minutes (Lemon Bottle) to 30 minutes (Aqualyx), depending on the area
Number of treatmentsAqualyx: usually 2 to 4 treatments spaced 3 to 4 weeks apart. Lemon Bottle: a series of treatments, with an interval of at least 7 days
ResultFirst changes after 2 to 3 weeks, full effect over the following one to two months
After treatment48 hours without direct sunlight, saunas and extreme temperatures

What exactly is lipolysis?

Lipolysis is an injection procedure that targets and removes fat deposits from areas where they persist most stubbornly – the double chin, stomach, flanks, and inner thighs. Using fine needles, a lipolytic cocktail is injected directly into the fat tissue. The active substances then stimulate the breakdown of fat cells, which are naturally eliminated from the body via the lymphatic system. Lipolysis is not a method for weight loss. It is intended for individuals who watch their diet and exercise regularly, yet are left with localised deposits on certain parts of the body that respond to neither diet nor physical activity. It is precisely these areas that lipolysis targets.

Fat removal using lipolysis

Every fat cell has a membrane that protects it and maintains its integrity. The active substances in the lipolytic cocktail act precisely on that membrane – destabilising it and encouraging the breakdown of the fat cell from within. The released fats are gradually removed and broken down by the body through normal metabolic pathways, primarily via the lymphatic system and the liver.

The process is not instant. The body gradually eliminates the broken-down fat cells in the weeks following the procedure. The first changes are usually noticed after two to three weeks, and the full effect develops over the following one to two months.

The result depends on the product, the area, the number of treatments and the tissue response, so it is assessed at the follow-up appointment. With a stable body weight, the change in the treated area can be long-lasting, but the remaining fat cells can enlarge again if weight increases.

Lipolysis is not for everyone – and that is important to say right away. The treatment is not intended for people who want to significantly reduce their body weight, but for those who are already close to their target weight yet are still bothered by certain areas.

Good candidates are people who exercise regularly and watch their diet, but whose double chin, stomach, flanks or inner thighs simply do not respond to the effort they put in. Lipolysis does not change the overall figure in these cases, but rather refines those details that spoil an otherwise good silhouette.

Each treatment is planned individually. At the initial consultation, the doctor assesses the amount and distribution of fatty tissue, the condition of the skin and the general health of the patient – only then is it determined whether lipolysis is the right solution and which preparation is best suited.

At Imedic poliklinika, we use two lipolytic products – Lemon Bottle and Aqualyx. They differ in composition, mode of action, target areas, number of treatments required and expected tissue response, so they should not be treated as interchangeable. The choice of product is always made individually, in consultation with a doctor, following an examination of the treated area.

Lemon Bottle is a lipolytic preparation whose formula is based on three active ingredients of natural origin – vitamin B2 (riboflavin), bromelain and lecithin, which work in synergy.

Vitamin B2 accelerates fat metabolism and acts as a catalyst in the lipolysis process. Bromelain is an enzyme derived from pineapple that has an anti-inflammatory effect and helps break down fat cells. Lecithin, obtained from soya, is a decisive factor in the destruction of the fat cell membrane, whilst simultaneously preventing adverse skin reactions.

One of the main advantages of the Lemon Bottle preparation is the minimal occurrence of swelling after application, making it particularly suitable for facial treatments – double chin, cheeks – but also for smaller body areas. The treatment can be repeated after just seven days.

Read more about this product on our page about Lemon Bottle.

Aqualyx is a product used for injection lipolysis. Its main active ingredient is deoxycholic acid, a molecule naturally found in our bodies whose role is to break down and absorb fat.

When injected into fat tissue, Aqualyx destroys the membrane of fat cells and turns them into tiny droplets which are then naturally eliminated from the body. As this is a substance the body already recognises, the process is gradual and well tolerated.

Aqualyx is particularly suitable for larger body areas – the stomach, flanks, thighs, upper arms – where the amount of fatty tissue is more pronounced and where a precise, deeper action of the preparation is required.

Lipolysis on its own removes fatty deposits – but the skin above the treated area must be firm enough for the result to look good. When fatty tissue diminishes and the skin lacks sufficient tone, sagging can occur which spoils the effect of the treatment. For this reason, lipolysis is rarely used as an isolated procedure in practice. Most frequently, it is part of a broader protocol that simultaneously addresses both fatty deposits and skin condition.

Examples of protocols:

  • Double chin: Lipolysis reduces fatty tissue under the chin, whilst Morpheus8 or Attiva simultaneously tighten the skin and improving its texture – preventing sagging after volume loss.
  • Larger body areas: on the stomach, flanks and thighs we combine lipolysis with body skin tightening treatments, such as Alma PrimeX and Morpheus8.

Lipolysis is used on areas where stubborn fat deposits persist despite physical activity and proper nutrition. At Imedic poliklinika, we treat:

  • Double chin – one of the most common indications; find out more on our page about Double chin removal.
  • Stomach – the lower part of the belly that remains a problem even for people with a normal body weight.
  • Flanks – localised fat deposits that barely respond to exercise.
  • Inner thighs – an area prone to fat accumulation regardless of physical activity.
  • Upper arms – excess fat on the inner arm that is difficult to lose through exercise.
Before the procedure itself, the doctor examines the area to be treated, assesses the amount and distribution of fat tissue and determines which product and quantity suit your case. Following this, the application is carried out – the lipolytic cocktail is precisely injected into the fatty tissue using fine needles. The treatment lasts between 15 and 30 minutes, depending on the region being treated. Immediately after the procedure, you can return to your daily routine. In the days that follow, mild redness, tenderness and swelling of the treated area are possible – this is an expected tissue reaction to the injection procedure. The symptoms usually resolve within a few days to two weeks.

Frequently asked questions about lipolysis

During the application, a pinprick is felt along with a brief stinging or burning sensation as the product begins to take effect. Anesthetic cream is used if necessary. Sensitivity to touch may last for several days.

For the Aqualyx product, usually 2 to 4 treatments spaced 3 to 4 weeks apart, and for the Lemon Bottle preparation, a series of treatments with an interval of at least 7 days. The number depends on the thickness of the deposit and is assessed during the follow-up.

The first changes can be seen after 2 to 3 weeks, and the full effect during the following month to two.

Broken-down fat cells do not return. The remaining cells can enlarge if body weight increases, so the result is most stable with a stable weight.

When the deposit under the chin is small and the skin is firm, lipolysis is often sufficient. When, alongside fatty tissue, there is also sagging skin, the doctor suggests Attiva radiofrequency or a combination with the Morpheus8 treatment. The decision is made after an examination, and all options are described on the page double chin removal.

During pregnancy and breastfeeding, in cases of skin infection or inflammation in the region, active malignant disease, and allergy to the ingredients of the preparation. Other conditions are assessed by a physician during the examination.

Cost of lipolysis

The prices for Lemon Bottle and Aqualyx treatments can be found on our Price list – body treatments. The exact price depends on the area and the quantity of product, and is determined after a consultation.

 

Book lipolysis in Belgrade

Imedic poliklinika is located at Kneza Miloša 23, 2nd floor, Belgrade. Opening hours: Monday–Sunday, 9:00–21:00.

Appointments can be booked by phone: 064 237 0707. If you contact us from abroad, we are also available via Viber and WhatsApp on the same number.

Author: Dr Ivica Jeremić

Author: Dr Ivica Jeremić

PhD in Medical Sciences (Molecular Medicine and Immunology), rheumatology subspecialist, dermatology resident.

Updated:

NOVEMBER OFFER · UNTIL 30.11.

Autumn for your skin

BOTOX (3 AREAS) + PROFHILO 2 ML
53.000 instead of 60.000

Morpheus8 face and neck
32.000 instead of 50.000

EMSCULPT – 6 TREATMENTS
85.000 instead of 105.000

LASER HAIR REMOVAL – FULL LEGS, BIKINI LINE, INTIMATE AREA AND UNDERARMS
15.000 instead of 18.000

Imedic poliklinika
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