Profhilo – in brief
| What is | Treatment with 64 mg of hyaluronic acid in 2 ml |
|---|---|
| What is being treated | Hydration, tone and elasticity of the skin of the face and neck |
| Anaesthesia | Anaesthetic cream |
| Number of treatments | Initially, usually two applications about a month apart; maintenance is individual |
| Result | The effects develop gradually over the coming weeks |
| Recovery | Possible redness, swelling, tenderness and bruising; the duration is individual |
| After treatment | 24 hours without makeup, intense physical activity, saunas, direct sun and alcohol |
What is Profhilo?
Profhilo contains 64 mg of hyaluronic acid in 2 ml, in the form of a high and low molecular weight complex. Its main goal is to improve skin quality, rather than precisely shaping an individual region like volumetric fillers do.
When are results visible after Profhilo injections?
The changes develop over the coming weeks. The initial plan usually involves two treatments spaced about a month apart, after which the effect on skin hydration and elasticity is assessed.
Profhilo treatment
How does Profhilo work?
Hyaluronic acid binds water and contributes to the hydration of the treated tissue. Profhilo is used in the approach biorevitalisation and skin quality improvement. It does not contain a vitamin and mineral cocktail, nor is its concentration proof of an immediate or guaranteed effect. An overview of various preparations can be found on the page Skin boosters.
What does a Profhilo treatment look like?
The treatment begins with a consultation and a discussion about what you would like to improve. The skin is cleansed and, if necessary, an anaesthetic cream is applied.
Profhilo is applied using the BAP (Bio Aesthetic Points) technique: at five points on each side of the face, making a total of ten. The points are chosen so that they are away from major blood vessels and nerves. Usually, 1 ml of the product is used for each side of the face.
In the first few hours, small bumps can be seen at the injection sites. These gradually subside as the product distributes evenly throughout the skin. The treatment takes a short time and afterwards you return to your daily routine.
Who is the Profhilo treatment for?
Profhilo can be considered for adults with dehydrated skin, fine lines and a mild loss of elasticity. An examination assesses whether the problem stems primarily from skin quality or from a loss of volume and support.
Age in itself is not an indication. If the main problem is the loss of supporting tissue, the doctor considers other options, including Profhilo Structura, when it is the appropriate choice.
What can you achieve with Profhilo?
Profhilo is an injectable treatment designed to hydrate and improve skin elasticity. It is most commonly chosen for the face and neck when the skin lacks freshness and firmness. Before the first treatment, we agree on the region and visit plan.
Which regions does it apply to?
Profhilo is most commonly applied to the face and neck. According to the doctor's assessment, it can also be applied to the décolletage and hands, where the skin also loses hydration and elasticity. For each region, the number of points and the amount of preparation are determined separately.
What are the benefits of the treatment?
A possible goal of the treatment is better hydrated skin, improved elasticity, and the softening of fine lines. The degree of change varies from person to person. Profhilo does not replace every wrinkle treatment, does not address all causes of sagging, and does not guarantee a facelift.
Profhilo or Profhilo Structura?
Profhilo focuses on skin hydration and elasticity. Profhilo Structura it is intended for a different purpose: changes in the superficial facial fat tissue and loss of support. A higher concentration of hyaluronic acid does not mean that one preparation is better for everyone. The choice depends on the tissue to be treated.
| Profhilo | Profhilo Structura | |
|---|---|---|
| Composition | 64 mg of hyaluronic acid in 2 ml | 90 mg of hyaluronic acid in 2 ml |
| What is being treated | Hydration, tone and skin elasticity | Superficial facial fat tissue and loss of support |
| Regions | Face and neck | Face |
| Initial plan | Two applications about a month apart | Two treatments four weeks apart |
Price of Profhilo treatment
You can view the price of the Profhilo skinbuster on the page. Price list.
Have you got a question?
Answers to frequently asked questions
Is the treatment painful?
Before the procedure, an anaesthetic cream is applied to make the treatment more comfortable. During application, a mild stinging sensation or pressure may be felt, but patients generally tolerate this well.
Is there a recovery period?
Following application, redness, swelling, tenderness and bruising may occur. Their duration varies among patients, so resolution within a few hours is not guaranteed. The doctor will provide instructions for aftercare and the resumption of activities. If severe or increasing pain, unusual skin discoloration or visual disturbances occur, seek medical attention immediately.
How many Profhilo treatments are required?
The initial cycle usually involves two applications about a month apart. The doctor adjusts the plan to the preparation, region and skin condition. Maintenance is agreed upon after assessing the response, without a universal promise that the result lasts for exactly six months.
Does Profhilo change the shape of the face?
No. Profhilo does not add volume and does not change facial features. The goal is skin quality: hydration, elasticity and a more even appearance. If the main problem is loss of volume or support, the doctor will suggest a different approach, for example hyaluronic fillers or Profhilo Structura.
Profhilo for neck rejuvenation
The skin on the neck is thinner and has fewer sebaceous glands, which is why it loses its elasticity more quickly. Profhilo can improve hydration, quality, and firmness of the neck skin, especially for fine lines and initial sagging. Profhilo is one of several treatments for this region, and an overview of all of them can be found on the page neck and décolletage treatments.
Profhilo, filler or skinbooster – what is the difference?
Profhilo, dermal fillers, and other skin boosters all contain hyaluronic acid, but they have different purposes.
| Profhilo | Hyaluronic filler | Other skinbusters | |
|---|---|---|---|
| Goal | skin hydration and elasticity | volume and shape of a given region | hydration and skin quality |
| Changes facial shape | What | yes, in the treated region | What |
| Method of application | 10 points (BAP) | precisely to the region being corrected | It depends on the product |
| Initial cycle | 2 applications, about a month apart | usually one, with a possible correction | It depends on the product |
Read more about fillers on the page hyaluronic fillers, and a comparison of skin quality products on the page skin boosters.
Profhilo and laser treatments
Combining with other procedures requires a separate plan and an appropriate time interval. Profhilo is not applied simultaneously with laser resurfacing or medium-depth chemical peels. The order of treatments and recovery is decided by the doctor according to the specific device and procedure.
A few tips after the treatment
For the first six hours, avoid applying pressure to the treated area. Drink plenty of fluids and care for your skin according to your doctor's instructions.
Potential side effects
They are most commonly temporary: redness, swelling, tenderness and bruising at the injection sites, which usually resolve within a few days. Lumps at the application sites occur less frequently.
In a review of practice data on over 40,000 patients, very few adverse reactions were reported and none were serious.
If you notice severe or increasing pain, a change in skin colour or visual disturbances, contact a doctor immediately.
How far in advance of the important event should I plan Profhilo?
We recommend planning your injectable treatment at least two weeks before an important event. If a series of treatments is required, the plan should start earlier to allow enough time for the full effect to develop.
Contraindications
The treatment is not performed during pregnancy and while breastfeeding, nor in cases of active skin infections, autoimmune diseases or known hypersensitivity to the ingredients of the preparation. Caution and a doctor's assessment are also required in cases of a tendency to keloids and blood clotting disorders.
Book a Profhilo treatment in Belgrade
The Imedic Polyclinic is located at Kneza Miloša 23 street, 2nd floor, Belgrade. Opening hours: Monday–Sunday, 9:00–21:00.
Appointments are made by phone: 064 237 0707. If you contact us from abroad, we are also available via Viber and WhatsApp on the same number.
Related topics
Author: Dr Ivica Jeremić
Doctor of Medical Sciences (Molecular Medicine and Immunology), subspecialist in rheumatology, dermatology resident.
Expert sources
- Laurino et al., 2015 — application technique and effect of hyaluronic acid hybrid complexes (Eplasty)
- Sparavigna and Tenconi, 2016 — efficacy and tolerability over 16 weeks (Clin Cosmet Investig Dermatol)
- Beatini and colleagues, 2016 — BAP (Bio Aesthetic Points) technique
- Cassuto et al., 2020 — real-world data safety (Biomed Res Int)
- Sparavigna et al., 2026 — a systematic review of the efficacy and safety of Profhilo
