PRX-T33 peel

PRX-T33 is a medical chemical peel that combines trichloroacetic acid (TCA), hydrogen peroxide and kojic acid. Unlike classic TCA peels, it does not cause marked skin peeling, and it acts in the deeper layers, where it stimulates renewal and collagen production. Because of this, it is often described as needle-free biorevitalisation. Below we explain how it works, who it is intended for, how …

PRX-T33
PRX-T33 is a medical chemical peel that combines trichloroacetic acid (TCA), hydrogen peroxide and kojic acid. Unlike traditional TCA peels, it does not cause pronounced skin peeling, and it works in the deeper layers, where it stimulates regeneration and collagen production. For this reason, it is often described as needle-free biorevitalisation. Below we explain how it works, who it is intended for, what the treatment looks like and what you can expect afterwards.

How does the PRX-T33 peel work?

TCA is present in PRX-T33 at a concentration of 33%, but is combined with hydrogen peroxide, which limits the peeling of the superficial layer of the skin. The acid therefore passes through the epidermis and acts on the dermis, where it stimulates fibroblasts to produce collagen and elastin, while the skin's surface remains intact. Collagen and elastin give the skin its firmness and elasticity, and their production decreases with age and with sun exposure. The regeneration of these fibres is seen as firmer, smoother and more even skin.

Composition: three active ingredients

  • TCA (trichloroacetic acid) penetrates the deeper layers of the skin and stimulates collagen production, thereby improving skin firmness and texture.
  • Hydrogen peroxide (H2O2) in this formula reduces the flaking and irritation that TCA would otherwise cause, so the skin does not look damaged after the treatment.
  • Kojic acid reduces melanin production and helps even out skin tone and fade dark spots.

Which skin concerns does PRX-T33 treat?

  • fine lines and loss of firmness in the skin of the face, neck and décolletage
  • uneven skin tone, dark spots and signs of sun damage
  • dull, greyish skin appearance and enlarged pores
  • shallow acne scars
The initial effect, fresher and firmer skin, is visible immediately after the treatment. The improvement in texture and firmness develops through a series of treatments.

PRX-T33 for dark spots and uneven skin tone

Kojic acid in the peel reduces melanin production, so PRX-T33 is also used for mild dark spots, post-acne marks, and a complexion that has become uneven after summer. After a series of treatments, the skin looks brighter and more even, and the blemishes become less pronounced. For melasma and more pronounced hyperpigmentation, the peel is usually only one part of the treatment plan, along with a dermatological examination and other treatments. Read more on our page about Hyperpigmentation and melasma.

Who is PRX-T33 for?

The peel is most commonly recommended for people whose goal is fresher, firmer and more even skin, and who cannot or do not want to have a recovery period with peeling. It also fits into combined plans, for example between sessions of microneedling, skin boosters or collagen stimulators. The treatment is not performed during pregnancy and breastfeeding, in the case of active herpes, open wounds or inflamed skin in the treatment area, nor in the case of hypersensitivity to any of the ingredients. For darker skin types and a tendency towards pigmentation, the doctor assesses the treatment plan with particular care.

How to prepare for the treatment?

For a week before the treatment, avoid scrubs, acid-based products and retinoids, and the skin should not be tanned or recently exposed to intense sun. If you are prone to cold sores, tell the doctor during the consultation so that the treatment can be planned accordingly. It is best to arrive for the treatment without makeup. If you have had any other facial aesthetic treatment in the preceding weeks, mention this to the doctor, as this determines when the peel can be performed.

What does the treatment involve?

The treatment begins with a skin examination and a discussion about what you want to improve. The skin is then thoroughly cleansed, and the PRX-T33 solution is applied in layers and rubbed in with massaging motions until it penetrates the skin. During application, you feel warmth and a mild stinging sensation, which quickly passes. After a few minutes, the peel is removed, and a cream that is part of the protocol is applied to the skin. The entire treatment takes about 15 to 30 minutes and can be performed on the face, neck, décolletage, and hands.

How many treatments are needed?

A course of three to five treatments spaced seven to fourteen days apart is most commonly recommended. The exact number depends on the condition of the skin and the goal, and is determined by a doctor during the consultation. The result is later maintained with individual treatments, in accordance with the doctor's recommendation.

Post-treatment recovery and care

Following the PRX-T33 peel, there is no significant peeling, so most patients return to their daily routines immediately. Mild redness or a feeling of tight skin may occur for a few hours, and in some individuals, a fine, barely noticeable flaking may occur over the next few days. For the first two to three days, gentle skincare without scrubs, acids, and retinoids is recommended, and sun protection is mandatory throughout the entire series of treatments. The treatment can be performed all year round, and the doctor times the appointment according to your skin type and sun exposure.

PRX-T33 or a classic TCA peel?

A classic TCA peel removes the surface layers of the skin and causes pronounced peeling, with a recovery time of five to seven days, which is why it is performed from October to the end of March. PRX-T33 uses TCA in a different way: it works in the deeper layers without damaging the surface, so there is no classic recovery period. The right peel for your skin is determined during an examination. Read more about all types of peels on our page about Chemical face peel.
Have a question?

Answers to frequently asked questions

During application, you feel warmth and stinging, which passes in a few minutes. Anaesthesia is not required.
Not to the same extent as after a traditional TCA peel. Mild flaking is possible, but the skin does not look damaged and there is no recovery period.

The treatment is used for a fresher and more even skin appearance and to improve its texture. The skin can appear smoother and more hydrated, while the course of treatments is tailored to the concerns you want to address.

Yes. Because it does not peel the skin like a classic TCA peel, PRX-T33 can be done all year round, with mandatory sun protection throughout the entire series. If you are planning a seaside holiday or intense sunbathing immediately after the treatment, let your doctor know so that you can choose a date together.

Yes, most often with microneedling, skin boosters and collagen stimulators. The order and interval between treatments are determined by the doctor.

PRX-T33 peel: price and booking

You can find the price of the PRX-T33 peel in our Price list. Appointments are booked by phone on 064 237 0707 or by email at imedic.rs@gmail.com.

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Dr Miloš Živković

Dr Miloš Živković

The Imedic team writes educational articles on dermatology, aesthetic medicine and skincare – clear, reliable information for patients.

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